Life may exist right under our noses in the Solar System—the moons of Jupiter and Saturn are of great interest. Europa and Enceladus may harbor vast subsurface oceans where at least microbial life could be possible. Thanks to new data obtained with the James Webb Space Telescope, scientists have discovered compelling evidence of extraterrestrial life on one exoplanet. But is water truly a necessary ingredient for life? A new study has determined that ionic liquids can form where liquid water cannot, thanks to their ability to remain liquid over a wide range of temperatures and pressures. These ionic liquids may ultimately support biomolecules such as proteins.